The Comparison of Interleukin-17 and Interleukin-10 with Systemic Lupus Erythematosus Disease Activity
نویسندگان
چکیده
منابع مشابه
Clinical associations of serum interleukin-17 in systemic lupus erythematosus
INTRODUCTION Serum interleukin (IL)-17 concentrations have been reported to be increased in systemic lupus erythematosus (SLE), but associations with clinical characteristics are not well understood. We characterized clinical associations of serum IL-17 in SLE. METHODS We quantified IL-17 in serum samples from 98 SLE patients studied cross-sectionally, and in 246 samples from 75 of these pati...
متن کاملCirculating interleukin-16 in systemic lupus erythematosus.
OBJECTIVE To investigate the relationship between interleukin (IL)-16 and systemic lupus erythematosus (SLE). METHODS Serum levels of IL-16 were examined in SLE patients using an enzyme-linked immunosorbent assay (ELISA). RESULTS The serum level of IL-16 in the patients was much higher than that in healthy volunteers (P < 0.001). An increase in IL-16 was observed in proportion to the activi...
متن کاملGenetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.
OBJECTIVE The aetiology of systemic lupus erythematosus (SLE) is incompletely understood. Both genetic and environmental factors are implicated in the pathogenesis of the disease. Herein, we describe genetic association between SLE and polymorphisms in the interleukin (IL)-21 gene. The reported effect of IL-21 on B-cell differentiation into plasma cells and its effect on dendritic cell maturati...
متن کاملSerum soluble interleukin 2 receptor in systemic lupus erythematosus: effects of disease activity and infection.
Serum soluble interleukin 2 receptor (sIL2R) was measured in patients with active and inactive systemic lupus erythematosus (SLE). The concentration of sIL2R was higher in inactive SLE than in normal controls and was significantly increased in active compared with inactive SLE. When patients with active SLE were followed up serially it was found that the sIL2R concentration fell when the diseas...
متن کاملSerum interleukin-17 levels are associated with nephritis in childhood-onset systemic lupus erythematosus
OBJECTIVES To determine the serum interleukin-17 (IL-17) levels in childhood-onset systemic lupus erythematosus patients and to evaluate the association between IL-17 and clinical manifestations, disease activity, laboratory findings and treatment. METHODS We included 67 consecutive childhood-onset systemic lupus erythematosus patients [61 women; median age 18 years (range 11-31)], 55 first-d...
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ژورنال
عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences
سال: 2020
ISSN: 1857-9655
DOI: 10.3889/oamjms.2020.4782