The counterattack of anti-HER2 small molecule compounds has started

Small Molecule Anti-Cancer Compounds Selectively Target the Hemopexin Domain of Matrix Metalloproteinase-9 (MMP-9)

Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Acknowledgements: We thank the members of the Sampson, Zucker and Cao labs for their insightful discussions and suggestions on the manuscript, and Kevin Zarrabi for his help with editing and Dr. Francis Johnson for his critical reading. We are also grateful to J. Shipman and T. Balius for their...

Pharmacist prescribing: has the momentum started?

At a March 2012 session in Calgary on legal liability related to expanded scope of practice, numerous pharmacists vehemently criticized the Alberta government for implementing, on July 1, 2012, payment to pharmacists for renewing prescriptions. The pharmacists were not criticizing the amount of the fee but, rather, the fact that they would have to perform the activity (i.e., renew prescriptions...

comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...

Has science started to go wrong?

The second year of the Journal of Hematopathology has started

The second year of the Journal of Hematopathology has started with this first and rich issue. The previous issue that was the first one printed, at the occasion of the Bordeaux Meeting of the EAHP and the SH, was very well received and contained the abstracts for the lymphoma and bone marrow symposium. That these two fields are really the pillars of Hematopathology is reflected by the two revie...