The effect of hydro-alcoholic Ferulago angulata extract on locomotor activity and anxiety caused by hypoperfusion ischemia in adult male rats

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Effects of Antidepressants Hydro-alcoholic extract of Chevilan (Ferulago angulate) in model of ischemia/ hypoperfusion in adult male rats

In patients with cerebral ischemia, both during hospitalization and in the community, the prevalence of major depression is evident. Since the depression has a negative impact on recovery, its timely diagnosis and treatment is essential. This study aimed to evaluate the effect of the oral administration of Chevilan extract (Ferulago angulata hydroalcoholic extract; 100, 200 and 400 mg/kg) on br...

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Hydroalcoholic Extract of Ferulago angulata Improves Memory and Pain in Brain Hypoperfusion Ischemia in Rats

BACKGROUND Cerebral ischemia causes some disorders in behavioral patterns, including memory disorders and pain, which is due to the production of free radicals. Ferulago angulata, known in Iran as chavir, contains some bioactive compounds having antioxidant and free radical-scavenging properties. OBJECTIVES This study aimed to evaluate the effect of two weeks oral administration of hydroalcoh...

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hydroalcoholic extract of ferulago angulata improves memory and pain in brain hypoperfusion ischemia in rats

conclusions ferulago angulata extract, because of its antioxidant activities, is probably capable of removing free radicals and oxidant substances from brain and thus it can improve behavioral disorders in brain hypoperfusion ischemia model. results it was found that the administration of 400 mg/kg hydroalcoholic extract of f. angulate for two weeks after brain hypoperfusion ischemia increased ...

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ژورنال

عنوان ژورنال: Journal of Herbmed Pharmacology

سال: 2017

ISSN: 2345-5004

DOI: 10.15171/jhp.2018.09