The Effects of Zileuton and Montelukast in Reperfusion-Induced Arrhythmias in Anesthetized Rats
نویسندگان
چکیده
منابع مشابه
The Effects of Zileuton and Montelukast in Reperfusion-Induced Arrhythmias in Anesthetized Rats☆
BACKGROUND 5-Lipoxygenase is an enzyme involved in the synthesis of leukotriene eicosanoids from arachidonic acid. The therapeutic potential of zileuton, an inhibitor of 5-lipoxygenase, and montelukast, a cysteinyl leukotriene receptor antagonist, for the treatment of ischemia/reperfusion (I/R) injury of the heart has been proposed in a few studies. However, the effects of zileuton and monteluk...
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ژورنال
عنوان ژورنال: Current Therapeutic Research
سال: 2013
ISSN: 0011-393X
DOI: 10.1016/j.curtheres.2013.06.001