The evolution of hemodynamic force parameters after cardiac resynchronization

Abstract Funding Acknowledgements Type of funding sources: None. Background A new mathematical model allows calculation hemodynamic forces (HDF) from routine transthoracic echocardiographic images. In large cohorts, the evolution HDF parameters in patients after onset cardiac resynchronization therapy (CRT) has not been investigated. Purpose To compare at baseline versus six months follow-up CRT implantation with non-ischemic cardiomyopathy. Methods Patients LV ejection fraction (LVEF) ≤35%, QRS duration ≥130 ms and left bundle branch block were included. complete heart cycle, following calculated: apical-basal strength (AB strength), lateral-septal (LS ratio LS to AB (LS-AB ratio) dominant angle (angle) (Figure 1). systolic thrust, impulse impulse) measured The measurements are presented as percentages, normalized for ventricular volume adjusted fluid density gravity acceleration. acquired implantation. Results 196 included (mean age 64 ± 11 years, 62% male). Clinical characteristics acquired, well (Table After a significant improvement occurred clinical (New York Heart Association class, Quality Life 6-minute walking distance) reverse remodeling (reduction atrial volumes increased LVEF global longitudinal strain). Moreover, change magnitude force, represented orientation observed. Conclusion evaluation shows an increase force force. This tool provides insight changes dynamics may contribute better understand benefit CRT.