The extracellular matrix of ovarian cortical inclusion cysts modulates invasion of fallopian tube epithelial cells
نویسندگان
چکیده
منابع مشابه
Skin metastases in epithelial ovarian and fallopian tube carcinoma
This study aimed to investigate the clinical features and outcomes of skin metastasis in ovarian and fallopian tube carcinomas.We studied patients with epithelial ovarian or fallopian tube carcinoma who developed skin metastasis from 2001 through 2012, and were also treated with chemotherapy and/or surgery.Skin metastases were classified as umbilical metastasis (Sister Joseph nodule [SJN]) and ...
متن کاملReconstitution of high-grade serous ovarian carcinoma from primary fallopian tube secretory epithelial cells
Fallopian tube secretory epithelial cells (FTSECs) have been suggested to be the source of high-grade serous ovarian carcinoma (HGSOC). Although several genetic alterations are known to be involved in HGSOC development, the minimal requirements remain unclear. We aimed to identify oncogenic mutations indispensable for HGSOC development in a stepwise model, using immortalized FTSECs. FTSECs were...
متن کاملEx Vivo Culture of Primary Human Fallopian Tube Epithelial Cells
Epithelial ovarian cancer is a leading cause of female cancer mortality in the United States. In contrast to other women-specific cancers, like breast and uterine carcinomas, where death rates have fallen in recent years, ovarian cancer cure rates have remained relatively unchanged over the past two decades (1). This is largely due to the lack of appropriate screening tools for detection of ear...
متن کاملEpithelial cells, Exracellular matrix
چکیده مقدمه: ماده خارج سلولی به عنوان بخش مهم ریز محیطMicroenvironment)(، نقش اساسی در نگهداری وضعیت تمایز دارد. در بررسیهای گذشته، این اثر در برخی سلولها از جمله سلولهای پوششی لوله رحم و یا رحم مطالعه شده است. در این پژوهشها، برای حفظ تمایز سلول ، علاوه بر ماده خارج سلولی عوامل دیگری مانند هورمونها، فاکتورهای رشد و سلولهای داربستی نیز بکار رفته است ولی فر...
متن کاملEpidermal inclusion cysts of the breast
AbstractEpidermal inclusion cysts are uncommon in the breast, but the consequences can besevere when these cysts occur in the breast parenchyma. Here, we report two suchcases. The patient in case 1 was an 37-year-old woman with a 3-cm palpable mass inthe right breast. Mammography revealed a round and smoothly outlined mass, whichindicated a benign tumor, and sonography showed an irregularly sha...
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ژورنال
عنوان ژورنال: APL Bioengineering
سال: 2018
ISSN: 2473-2877
DOI: 10.1063/1.5022595