The first reported paramutation
نویسندگان
چکیده
منابع مشابه
Paramutation: The Chromatin Connection
Paramutation has been studied extensively in maize since R.A. Brink described a heritable alteration of the r locus that defied principles of Mendelian inheritance (Brink, 1956). A recent publication on paramutation in maize now provides convincing evidence that chromatin-level regulation underlies the phenotypic differences between alleles that participate in paramutation (Stam et al., 2002a)....
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متن کاملFrom Paramutation to Paradigm
Classical genetic studies aim to understand how genes determine biological processes, physical characteristics, behaviour, and disease by identifying heritable variations in DNA sequence that associate with specific phenotypes. However, organisms ranging from plants to mammals also possess some characteristics that can be inherited in the absence of any causal genetic variant [1,2]. Examples of...
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Paramutation is the epigenetic transfer of information from one allele of a gene to another to establish a state of gene expression that is heritable for generations. RNA has recently emerged as a prominent mediator of this remarkable phenomenon in both maize and mice.
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ژورنال
عنوان ژورنال: Journal of Genetics
سال: 2022
ISSN: ['0973-7731', '0022-1333']
DOI: https://doi.org/10.1007/s12041-021-01352-9