The hierarchical organization of the lateral prefrontal cortex

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The hierarchical organization of the lateral prefrontal cortex.

Higher-level cognition depends on the lateral prefrontal cortex (LPFC), but its functional organization has remained elusive. An influential proposal is that the LPFC is organized hierarchically whereby progressively rostral areas of the LPFC process/represent increasingly abstract information facilitating efficient and flexible cognition. However, support for this theory has been limited. Here...

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Human thought is a remarkable evolutionary achievement and one of our species’ defining abilities. It has been closely linked to the prefrontal cortex (PFC) by converging evidence from a wide range of disciplines, from phylogenetic and ontogenetic development, to patient studies and single-cell recordings, to modern neuroimaging. Here I review work on the links between the lateral PFC and two d...

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ژورنال

عنوان ژورنال: eLife

سال: 2016

ISSN: 2050-084X

DOI: 10.7554/elife.12112