The Impact of Early Institutionalization Experience on Child Development: Biological Indicators, Physiological Mechanisms, Behavioral Characteristics

<p style="text-align: justify;"><strong>Objective. </strong>Systematization and generalization of research data on the impact early institutionalization biological indicators children's development, a description underlying physiological mechanisms relations between their behavioral manifestations in children.</p> justify;"><strong>Background. </strong>Early deprivation is significant social-psychological factor that dramatically affects subsequent mental health development children. To date, wide amount effects institutional has been accumulated literature while this information little represented Russia. understand specificity children with experience transferred from Russian institutions into domestic adoptive or foster care families there need to analyze, systematize generalize bio-behavioral consequences institutionalization.</p> justify;"><strong>Conclusions. </strong>Research results indicate change manifested negative changes morphofunctional microstructural organization brain, characteristics its activity, cortisol secretion, violations immunity, DNA methylation profiling, microbiome. Biological correlates are associated such conditions as severity duration (the age child's transfer institution family). In order prevent developmental, somatic disorders long-term deprivation, state policy field childhood work professional society have fulfil rights child live family relationship sensitive responsive emotionally available primary caregivers.</p>