The Importance of Subgroup Analysis in Drug-Eluting Stent Trials
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چکیده
منابع مشابه
The Importance of Subgroup Analysis in Drug-Eluting Stent Trials.
SEE PAGE 28 C ardiovascular drugs and devices may have different safety and efficacy profiles in certain populations. Performance of separate trials or subgroup analysis is important if there is a biological reason, either intrinsic and/or extrinsic, for a varied response to a therapy. For example, compared with men, women have different body size, hormonal milieu, sex-specific physiology, and ...
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5-lipoxygenase gene disruption reduces amyloidpathology in a mouse model of Alzheimer’s disease. FASEB J 2008;22:1169 –78. 6. Manev R, Imbesi M, Uz T, Dzitoyeva S, Dimitrijevic N, Manev H. Effects of 5-lipoxygenase inhibitors MK-886 and caffeic acid in a model of forced swimming in wild-type and 5-lipoxygenase– deficient mice. Program 711.4/BB17. 2007 Neuroscience Meeting Planner. San Diego, CA...
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اندیشمندان و صاحب نظران علوم اجتماعی بر این باورند که مرحله تازه ای در تاریخ جوامع بشری اغاز شده است. ویژگیهای این جامعه نو را می توان پدیده هایی از جمله اقتصاد اطلاعاتی جهانی ، هندسه متغیر شبکه ای، فرهنگ مجاز واقعی ، توسعه حیرت انگیز فناوری های دیجیتال، خدمات پیوسته و نیز فشردگی زمان و مکان برشمرد. از سوی دیگر قدرت به عنوان موضوع اصلی علم سیاست جایگاه مهمی در روابط انسانی دارد، قدرت و بازتولید...
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We thank Dr. Shanmugam for his interest in our study (1). Most of the limitations he raises have been discussed in detail in our report. We have never suggested that a cutoff of 40 mm Hg was equivalent to severe pulmonary hypertension. Nonetheless, as we have also alluded to in our study, such levels of pulmonary pressures, equivalent to mild/moderate pulmonary hypertension, have been associate...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Interventions
سال: 2016
ISSN: 1936-8798
DOI: 10.1016/j.jcin.2015.11.006