The neutrophil-lymphocyte ratio and immunosuppressive acidic protein may be useful parameters for predicting depression among middle-aged patients with diffuse large B cell lymphoma

Background Patients with diffuse large B cell lymphoma (DLBCL) may experience depression. Growing evidence shows that depression interacts immunity. However, the relationship between and immunity among DLBCL patients has not been investigated, despite reports indicating often suffer from Methods To accurately investigate immunity, 82 primarily diagnosed middle-aged who received standard chemotherapy were enrolled. The divided into depressed nondepressed groups according to Zung Self-rating Depression Scale (SDS) scores. Prozac was used treat until their symptoms alleviated. concentration of immunosuppressive acidic protein (IAP); percentages cluster differentiation (CD)3+, CD4+, CD8+ T lymphocytes CD56+ natural killer (NK) cells; absolute lymphocyte count (ALC); neutrophil--lymphocyte ratio (NLR) calculated at enrollment after treatment. Results A higher score on test positively associated serum IAP levels NLR, negatively ALC. NLR in significantly compared those patients. Conclusions Our results suggest for first time are closely correlated be parameters predicting