The Rate-determining Step in P450 C21-catalyzing Reactions in a Membrane-reconstituted System
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چکیده
منابع مشابه
The rate-determining step in P450 C21-catalyzing reactions in a membrane-reconstituted system.
Adrenal cytochrome P450 C21 in a membrane-reconstituted system catalyzed 21-hydroxylation of 17alpha-hydroxyprogesterone at a rate higher than that for progesterone in the steady state at 37 degrees C. The rate of product formation in the steady state increased with the concentration of the complex between P450 C21 and the reductase in the membranes. The complex formation was independent of the...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2001
ISSN: 0021-9258
DOI: 10.1074/jbc.m006043200