The requirement of reactive oxygen intermediates for lymphocytic choriomeningitis virus binding and growth
نویسندگان
چکیده
منابع مشابه
Lymphocytic Choriomeningitis Virus
There has been an upsurge of interest in lymphocytic choriomeningitis virus (LCMV) as a human pathogen and specifically as an underdiagnosed congenital infection (1,2). LCMV is a member of the Arenaviridae family of viruses. Arenaviruses have a complex life cycle involving chronic infection and shedding of the virus in rodents and episodic infections in humans (3,4). Six of the arenaviruses (La...
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The biological relevance of nonneutralizing antibodies elicited early after infection with noncytopathic persistence-prone viruses is unclear. We demonstrate that cytotoxic T lymphocyte-deficient TgH(KL25) mice, which are transgenic for the heavy chain of the lymphocytic choriomeningitis virus (LCMV)-neutralizing monoclonal antibody KL25, mount a focused neutralizing antibody response following...
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Lung contusions and pandemic (H1N1) 2009 can cause ARDS (6,7). We do not know the relative role of each in causing the ARDS that our patient had, but the severity of clinical symptoms, although the lung injury was judged to be only of moderate magnitude, suggests that infl uenza played a major role in the development of his acute lung disease. The infection with oseltamivir-resistant virus, for...
متن کاملRetroviral vectors pseudotyped with lymphocytic choriomeningitis virus.
Pseudotyping can improve retroviral vector stability and transduction efficiency. Here, we describe a novel pseudotype of murine leukemia virus packaged with lymphocytic choriomeningitis virus (LCMV). This pseudotype was stable during ultracentrifugation and infected several cell lines from different species. Moreover, LCMV glycoproteins were not cell toxic.
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ژورنال
عنوان ژورنال: Virology
سال: 2008
ISSN: 0042-6822
DOI: 10.1016/j.virol.2008.07.004