The Structural Abnormality of Hemoglobin Mankakee

a structural survey of the polish posters

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The abnormality of the primary structure of hemoglobin Shimonoseki.

Received April2, 1965 In 1960 Yamaoka et al. described one of the first well-documented abnormal hemoglobins to be found in Japan. This hemoglobin, designated Hb Shimonoseki for the city in which the family resides, constitutes approximately 20% of the hemoglobin of the heterozygotes and migrates with Hb S on paper electrophoresis at pH 8.6. The present communication concerns its further charac...

Abnormality of hemoglobin molecules in hereditary hemolytic anemias.

Characterization of a chemical abnormality in hemoglobin G.

The development of methods (3,4) for localizing the differences in the primary structure of the human hemoglobins has prompted a study of the differences between the structures of hemoglobins A, S, and G. Knowledge of the structural differences might give new insight into the genetic control of the structure of these hemoglobins (5, 6). The results of this study, which are presented here, indic...

A new inherited abnormality of hemoglobin and its interaction with sickle cell hemoglobin.

V. NEEL, M.D., PH.D. T HIS REPORT deals with a new inherited abnormality of hemoglobin encountered in American Negroes. The existence of this traitcame to light ill the course of extensive clinical and genetic studies u’egarding the sickling pheuiomenon. Among the individuals examined thei’e were anumber of patients ‘it-h a hemolytic syndrome associated with erythrocytic sickling in whom neithe...