THE SYNTHESIS IN VIVO OF LACTOSE FROM GLUCOSE-1-C14 AND GALACTOSE-1-C14 IN THE GUINEA PIG
نویسندگان
چکیده
منابع مشابه
Synthesis of D-Glucose-1-C14 and D-Mannose-1-C14
Heretofore, radiochemical yields of sugars position-labeled with carbon-14 have been only 5 to 10 percent. This paper reports an improved cyanohydrin synthesis, and the preparation of D-glucose-1-C and D-mannose-1-C from D-arabinose in yields of about 50 percent. Low yields in prior syntheses appear to have been due to several inefficient steps, and to the fact that extension of the carbon chai...
متن کاملLactose synthesis in the mammary gland perfused with 1-C14-glucose.
The problem of lactose synthesis in the mammary gland is two-fold: (a) the mechanism by which galactose is formed and (b) the mechanism of condensation of t’he monosaccharide precursors to form the disaccharide. Several mechanisms for the glucose-galactose interconversion in nature have been postulated: (a) Walden inversion of the hydroxyl on carbon atom 4 of glucose (Rohman (I), Robinson (a), ...
متن کاملComparison of the metabolism of C14-labeled lactose, glucose, and galactose in rats.
The importance of milk in human nutrition makes it desirable to understand better the metabolism of lactose. Much of the experimental work on the utilization of lactose has been conducted with rats (8, 16). Other investigators have employed pigs, chickens, dogs, and calves (10-12, 19), while infants, children, and adults were used under suitable conditions (2, 14, 21, 23). We wish to report her...
متن کاملThe biosynthesis of glucuronic acid from 1-C14-glucose.
Although many classes of substances found in the animal organism have been suggested as possible biological precursors of glucuronic acid (l), recent research has narrowed the number of these possibilities to two, namely hexoses (2,3) and trioses (4, 5). Various experimental techniques, including isotopic tracers, have been used in the effort to choose between these alternatives, but invariably...
متن کاملConversion of glucose-1-C14 to pectin in the boysenberry.
Many authorities believe that pectins play a dominant r&e in the changes in texture of fruits during the ripening process, although the origin and fate of pectic substances in plant tissues are unknown ((1) p. 273). There is no evidence that in nature pectic substances are formed directly from galactose or galactan ((1) p. 277). To obtain some insight into the mechanism of pectin formation, glu...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)65037-9