The Target of Daptomycin Is Absent from Escherichia coli and Other Gram-Negative Pathogens
نویسندگان
چکیده
منابع مشابه
The target of daptomycin is absent from Escherichia coli and other gram-negative pathogens.
Antistaphylococcal agents commonly lack activity against Gram-negative bacteria like Escherichia coli owing to the permeability barrier presented by the outer membrane and/or the action of efflux transporters. When these intrinsic resistance mechanisms are artificially compromised, such agents almost invariably demonstrate antibacterial activity against Gram negatives. Here we show that this is...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2012
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.02005-12