The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain
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چکیده
منابع مشابه
The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain
Cdc13, the telomere end-binding protein from Saccharomyces cerevisiae, is a multidomain protein that specifically binds telomeric single-stranded DNA (ssDNA) with exquisitely high affinity to coordinate telomere maintenance. Recent structural and genetic data have led to the proposal that Cdc13 is the paralog of RPA70 within a telomere-specific RPA complex. Our understanding of Cdc13 structure ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2013
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkt843