The Transition between Transcriptional Initiation and Elongation in E. coli Is Highly Variable and Often Rate Limiting
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چکیده
منابع مشابه
The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate limiting.
We perform a genome-wide analysis of the transition between transcriptional initiation and elongation in Escherichia coli by determining the association of core RNA polymerase (RNAP) and the promoter-recognition factor sigma70 with respect to RNA transcripts. We identify 1286 sigma70-associated promoters, including many internal to known operons, and demonstrate that sigma70 is usually released...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2006
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2006.10.030