The Treatment of Multiple Sclerosis with Beta-Interferon

P 52: Interferon beta-a1 vs. Teriflunomide for Multiple Sclerosis

Multiple sclerosis (MS) is an inflammatory disorder, in which neurons in central nervous system (CNS) become demyelinated .MS is named for its formation of plaques due to sclerosis of myelin. Variable degree of demyelination results in mild, mediate or severe symptomatic episodes of this disease. It is commonly characterized by recurrent relapses and often followed by severe neurological disabi...

[Interferon-beta in the treatment of multiple sclerosis].

Inhibitory effect of the interferon-beta on the release of endothelial cell derived microparticles in patients with multiple sclerosis

Abstract Introduction: Increased levels of microparticles (MPs) have been reported in many autoimmune diseases such as multiple sclerosis (MS). In MS, endothelial cells release MPs from their membranes following the activation of lymphocytes and the production of inflammatory cytokines. The aim of this study was to investigate the inhibitory effect of interferon beta (INFβ) on the release of en...

Fulminant liver failure during interferon beta treatment of multiple sclerosis.

Although interferon (IFN) b has many adverse effects, including flulike illness, increased spasticity, and laboratory abnormalities,1 autoimmune events are usually limited to autoantibodies with the thyroid the most common target organ involved.2 Liver abnormalities during IFN b therapy are usually clinically asymptomatic and transient biochemical events.1,2 We report a patient who developed ac...

Interferon-beta Treatment in Multiple Sclerosis: Analysis of Neutralizing Antibodies