The Triggering Receptor Expressed on Myeloid Cells 2: “TREM-ming” the Inflammatory Component Associated with Alzheimer's Disease
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The Triggering Receptor Expressed on Myeloid Cells 2: “TREM-ming” the Inflammatory Component Associated with Alzheimer's Disease
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by a progressive loss of memory and cognitive skills. Although much attention has been devoted concerning the contribution of the microscopic lesions, senile plaques, and neurofibrillary tangles to the disease process, inflammation has long been suspected to play a major role in the etiology of AD. Recently, a n...
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GREGORY R TINTINGER*, VAN DER MERWE JJ*, FICKL H°, RHEEDER P*, FELDMAN C, ANDERSON R° *Department of Internal Medicine, Faculty of Health Sciences, University of Pretoria, South Africa; °Medical Research Council Unit for Inflammation and Immunity, Department of Immunology, University of Pretoria, and Tshwane Academic Division of the National Health Laboratory Service, Pretoria, South Africa; an...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2013
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2013/860959