The Use of Bromodeoxyuridine-Immunohistochemistry to Identify Transplanted Fetal Brain Tissue
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چکیده
منابع مشابه
The Use of Bromodeoxyuridine-Immunohistochemistry to Identify Transplanted Fetal Brain Tissue
The immunohistochemical detection of the thymidine analog, 5-bromo-2'-deoxyuridine (BrdU) is shown to be a useful and reliable method to positively identify fetal brain transplants in standard histological preparations. This technique offers several advantages over the [3H]thymidine autoradiographic method, including being much more rapid and avoiding the use of radionuclides.
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Determining the birthdate of neurons and glia in relation lO the time period of neurochemical 1.nd cellular differentiation are necessary for understanding early developmental events in the central nerv.>us system (CNS). Bromodeoxyuridine (BrdU). a thymidine analog has recently become an alternative to the tritiated thymidine autoradiography for the study of cytogenesis in the CNS. Our laborato...
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ژورنال
عنوان ژورنال: Journal of Neural Transplantation
سال: 1989
ISSN: 1352-237X
DOI: 10.1155/np.1989.135