The Usefulness of Component-Resolved Diagnostics in Food Allergy

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The Usefulness of Component-Resolved Diagnostics in Food Allergy

© Copyright The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://e-aair.org The gold standard for the diagnosis of IgE-mediated food allergy is an oral food challenge (OFC) that directly verifies the causal relationship between clinical symptoms and offending foods. However, OFC carries a risk of developing fatal ...

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PURPOSE OF REVIEW Component-resolved diagnostics makes use of defined allergen molecules to analyse IgE-mediated sensitizations at a molecular level. Here, we review recent studies on the use of component-resolved diagnostics in the field of Hymenoptera venom allergy (HVA) and discuss its benefits and limitations. RECENT FINDINGS Component resolution in HVA has moved from single molecules to ...

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FOOD ALLERGY Clinical Value of Component-Resolved Diagnostics in Peanut-Allergic Patients

METHODS. The Auvi-Q and EpiPen were evaluated by each participant in a randomly assigned order. Participantswere given a scenario that involved anaphylaxis and were instructed to simulate the use of each device using trainers that did not have a needle or contain epinephrine. Subjects were expected to perform the device test by relying on the labeling and/or voice instruction or intuition to pe...

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Component-resolved diagnosis of plant food allergy by SPT.

BACKGROUND Fruits and vegetables may contain both labile and stable allergens. The former induce only OAS, whereas stable allergens may induce systemic reactions. Component-resolved diagnosis (CRD) of allergy to plant foods is therefore essential for the clinical management of allergic patients. METHODS 80 adults allergic to plant foods underwent SPT with purified natural date palm profilin (...

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Food allergy and anaphylaxis – 2044. Component resolved allergen sensitzation profiles in shrimp allergy in the tropics

Methods Serum allergen-specific IgE of 105 subjects were quantified using ImmunoCAP and ImmunoCAP ISAC biochips. The subjects were classified based on a convincing clinical history and food challenge testing (FC) (dose=70g) to Penaeus monodon and Litopenaeus vannamei. Group1A: Either SA with FC positive to either shrimp (n =22) or SA admitted to emergency departments for severe reactions but no...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Immunology Research

سال: 2014

ISSN: 2092-7355,2092-7363

DOI: 10.4168/aair.2014.6.2.103