The value of interleukin-6 (IL-6) within 6 hours after birth in the prompt diagnosis of early-onset neonatal sepsis
نویسندگان
چکیده
منابع مشابه
Immediate Diagnosis of Early Onset Sepsis in Premature Newborns by Measurement of Cord C-Reactive Protein and Interleukin-6
Background: The purpose of this study was to determine the relationship between early onset sepsis and increased levels of C-reactive protein (CRP) and interleukin-6 (IL-6) in cord plasma. Methods: A prospective study was conducted in 141 premature infants delivered with gestational ages of 26-35 weeks. IL-6 and CPR were measured by enzyme-linked immunoassay in the cord plasma of the neonates. ...
متن کاملevaluation of interleukin-6 for early diagnosis of neonatal sepsis in comparison with crp
introduction early diagnosis of neonatal sepsis is essential for successful treatment. blood culture is a gold standard for diagnosis but the final results are not available until 48-72 hours after culture. interleukin-6 (il-6) as a marker plays a critical role in the induction of c-reactive protein (crp) synthesis in the liver. it has been hypothesized that this cytokine could be detected in b...
متن کاملDiagnostic Value of IL-6 in Neonatal Sepsis
Background: Neonatal sepsis is a serious life-threatening condition with high mortality. The early and accurate diagnosis of sepsis is one of main challenge for prevention of mortality due to sepsis in NICUs. A great effort to reduce the neonatal mortality rate is put into looking for new reliable biomarkers. Among various biomarkers, IL-6 could be promising and reliable biomarker for early dia...
متن کاملReactive hyperemia and interleukin 6, interleukin 8, and tumor necrosis factor-alpha in the diagnosis of early-onset neonatal sepsis.
OBJECTIVE To evaluate the diagnostic value of peripheral circulatory reactive hyperemia and serum levels of interleukin-6 (IL-6), IL-8, and tumor necrosis factor-alpha (TNF-alpha) in early-onset neonatal sepsis. METHODS Reactive hyperemia in the dorsal hand and serum levels of IL-6, IL-8, and TNF-alpha were studied in newborn infants (n = 32; gestational age 39 +/- 3 weeks) who had been admit...
متن کاملReactive Hyperemia and Interleukin 6, Interleukin 8, and Tumor Necrosis Factor- in the Diagnosis of Early-Onset Neonatal Sepsis
Objective. To evaluate the diagnostic value of peripheral circulatory reactive hyperemia and serum levels of interleukin-6 (IL-6), IL-8, and tumor necrosis factor(TNF) in early-onset neonatal sepsis. Methods. Reactive hyperemia in the dorsal hand and serum levels of IL-6, IL-8, and TNFwere studied in newborn infants (n 32; gestational age 39 3 weeks) who had been admitted to the neonatal unit b...
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ژورنال
عنوان ژورنال: Translational Pediatrics
سال: 2020
ISSN: 2224-4336,2224-4344
DOI: 10.21037/tp-20-239