The vesicular trafficking system component MIN7 is required for minimizing <i>Fusarium graminearum</i> infection

Abstract Plants have developed intricate defense mechanisms, referred to as innate immunity, defend themselves against a wide range of pathogens. often respond rapidly pathogen attack by the synthesis and delivery primary infection sites various antimicrobial compounds, proteins, small RNA in membrane vesicles. Much evidence regarding importance vesicular trafficking plant–pathogen interactions comes from studies involving model plants whereas this process is relatively understudied crop plants. Here we assessed whether system components previously implicated immunity Arabidopsis play role interaction with Fusarium graminearum, fungal well-known for its ability cause head blight disease wheat. Among analysed mutants, two independent T-DNA insertion mutants AtMin7 gene displayed markedly enhanced susceptibility F. graminearum. Earlier identified gene, encoding an ARF-GEF protein, target HopM1 effector bacterial Pseudomonas syringae pv. tomato, which destabilizes MIN7 leading degradation weakening host defenses. To test key component may also contribute plants, candidate TaMin7 genes wheat knocked-down their expression through virus-induced silencing. Wheat were silenced significantly more disease. This suggests that disruption function both compromises signals or products resulting hypersusceptibility