Thymineless Death in Escherichia coli: Inactivation and Recovery
نویسندگان
چکیده
منابع مشابه
Thymineless death in Escherichia coli.
There is little doubt that thymine starvation af fects the DNA of thymine requiring bacteria1-5. However, the process of killing is fairly complicated and remains to be clarified. The genes responsible for the control of sensitivity to thymine starvation have not been identified, even though claims have been but forward for at least one gene6. Besides, whether the cells die when still in incub...
متن کاملThymineless death in polA+ and polA- strains of Escherichia coli.
The extreme sensitivity of polA(-) cells to thymineless death is due, primarily, to the absence of an extended lag prior to the commencement of death. Once thymineless death has commenced, the rate in polA(-) cells is only slightly faster than in polA(+) cells.
متن کاملEnergy Requirement for Thymineless Death in Cells of Escherichia Coli.
Freifelder, David (University of California, Berkeley), and Ole Maaløe. Energy requirement for thymineless death in cells of Escherichia coli. J. Bacteriol. 88:987-990. 1964.-Thymineless death in thymine-requiring Escherichia coli is arrested immediately and reversibly by nitrogenation if the bacterial population is growing in a medium containing a carbon source that can only be metabolized aer...
متن کاملThymineless death in Escherichia coli 15T- and recombinants of 15T- and Escherichia coli K-12.
Thymineless death was examined in Escherichia coli 15T(-) and recombinants of 15T(-) and E. coli K-12. Those strains that were very sensitive to thymine deprivation were also very sensitive to a variety of inducing agents (mitomycin C, ultraviolet light, hydroxyurea, and nalidixic acid). Those strains that were relatively resistant to thymineless death were also relatively resistant to the indu...
متن کاملThymineless death in recombination deficient mutants of Escherichia coli K12.
When grown in thymine-free minimal synthetic medium, thyA recA mutants of Escherichia coli K12 were comparatively more resistant and thyA recBC mutants more sensitive to thymineless death (TLD) than their respective parent strains. No excessive numbers of single-strand breaks were observed in the DNA of the recBC mutant strain starved for thymine, hence the hypersensitivity for TLD in this stra...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1969
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.99.2.558-566.1969