Time- and depth-dependent changes to articular cartilage mitochondrial content occur during the 48 hours after injury
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چکیده
منابع مشابه
Spatial and depth dependent viscoelastic behavior of articular cartilage
The mechanical response of the soft tissues of the knee is nonlinear, anisotropic, and viscoelastic. Individual tissues may also express nontrivial gradients of material properties throughout their structure, adding to the modeling complexity of the anatomy. Computational models of whole knee biomechanics can be extremely useful in understanding the progression of degenerative diseases and trau...
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INTRODUCTION Articular cartilage (AC) is an inhomogeneous, anisotropic and multiphasic composite. Depth-dependent strain distribution in full thickness AC has previously been investigated with optical methods (Guilak, 1995; Schinagl, 1997; Wang, 2003). Depth and time-dependent compressive strain has been predicted with theoretical models (Li, 2000; Wang, 2001). Most recently, Electronic Speckle...
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The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...
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The cardiac rate and rhythm were studied by 24-hour ambulatory electrocardiographic recording in 44 patients before, during, and after being discharged from hospital following an acute myocardial infarction. The first recordings were started 48 hours before discharge, the second on the morning of the day of discharge, and the third 48 hours after discharge (at home). While in hospital and after...
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Articular cartilage lesions in the athletic population are observed with increasing frequency and, due to limited intrinsic healing capacity, can lead to progressive pain and functional limitation over time. If left untreated, isolated cartilage lesions can lead to progressive chondropenia or global cartilage loss over time. A chondropenia curve is described to help predict the outcome of carti...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2020
ISSN: 1063-4584
DOI: 10.1016/j.joca.2020.02.292