Tissue microarrays for predictive molecular pathology
نویسندگان
چکیده
منابع مشابه
Introducing tissue microarrays to molecular pathology.
Featured Article: Tissue microarrays for highthroughput molecular profiling of tumor specimens. Kononen J, Bubendorf L, Kallioniemi A, Bärlund M, Schraml P, Leighton S, Torhorst J, Mihatsch MJ, Sauter G, Kallioniemi OP. Nat Med. 1998;4:844 –7. Tissue specimens are essential for biomedical and clinical research. In situ detection of DNA, RNA, and protein targets in tissues provides a powerful me...
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a long-lasting problem in the analysis of tissue samples is the time-consuming and repetitive process of histologic preparation and pathologic review of tissue sections. these two critical factors, innate nonuniformity in preparation and subjectivity of analysis, therefore limit the scientific and statistical thoroughness of tissue based studies. employing tissue microarray (tma) technique prov...
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The TMA is a high-throughput technique to assess thousands of different cores of pathological tissue simultaneously using morphological and molecular analyses, e.g. immunohistochemistry and in situ hybridization, whilst maintaining an accurate and efficient method of identifying each specific section. Using this technique an economy in cutting and staining can also be used, with an unprecedente...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2002
ISSN: 0021-9746
DOI: 10.1136/jcp.55.8.575