Tissue Microarrays in Clinical Oncology
نویسندگان
چکیده
منابع مشابه
Clinical application of cDNA microarrays in oncology.
DNA microarrays represent an important new tool to analyze human tissues. The technology enables investigators to measure the expression of several thousand mRNA species simultaneously in a biological specimen. This process, called transcriptional profiling, represents a technological breakthrough in the analysis of biological specimens. It may be used to screen for individual genes that are di...
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a long-lasting problem in the analysis of tissue samples is the time-consuming and repetitive process of histologic preparation and pathologic review of tissue sections. these two critical factors, innate nonuniformity in preparation and subjectivity of analysis, therefore limit the scientific and statistical thoroughness of tissue based studies. employing tissue microarray (tma) technique prov...
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The TMA is a high-throughput technique to assess thousands of different cores of pathological tissue simultaneously using morphological and molecular analyses, e.g. immunohistochemistry and in situ hybridization, whilst maintaining an accurate and efficient method of identifying each specific section. Using this technique an economy in cutting and staining can also be used, with an unprecedente...
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Tissue microarray technology (TMA) is a relatively new approach for efficiently and economically assessing protein and gene expression across large ensembles of tissue specimens. Tissue microarray technology holds great potential for reducing the time and cost associated with conducting research in tissue banking, proteomics, and outcome studies. However, the sheer volume of images and other da...
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ژورنال
عنوان ژورنال: Seminars in Radiation Oncology
سال: 2008
ISSN: 1053-4296
DOI: 10.1016/j.semradonc.2007.10.006