To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture
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To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture
Induced pluripotent stem cells (iPSCs) are usually clonally derived. The selection of fully reprogrammed cells generally involves picking of individual colonies with morphology similar to embryonic stem cells (ESCs). Given that fully reprogrammed cells are highly proliferative and escape from cellular senescence, it is conceivable that they outgrow non-pluripotent and partially reprogrammed cel...
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Many new reproductive methods such as artificial insemination, in vitro fertilisation, freezing of human embryos, and surrogate motherhood were at first widely condemned but are now seen in Western society as not just ethically and morally acceptable, but beneficial in that they allow otherwise infertile couples to have children. The idea of human cloning was also quickly condemned but debate i...
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Creating exact copies (clones) of an individual has long been a made-to-believe story in various cultures throughout mankind history. However, the report of successfully creating a genetic clone of an adult animal from a differentiated somatic cell [1] completely shocked the world. The cloning technology involves taking the nucleus from a somatic cell and then inserting that nucleus into an unf...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0065324