To Determine the Effect of Prothrombin Time (PT), Activated Partial Thrombopalstin Time (APTT), and International Normalized Ratio (INR) Levels on Gender and Age

Background: Hepatic function, coagulation disorders, and the risk of postoperative bleeding can all be detected with PT assay. When it comes to measuring "extrinsic route" factors, is most commonly used test. It possible check for a lack intrinsic or common route factors by duration trigger partial thromboplastin (aPTT). A solution problem inconsistent measurements among laboratories was creation International Normalized Ratio (INR). Laboratory-specific reference intervals have significant impact on quality patient treatment influencing clinical decision-making. Objective: The purpose this study determine if gender age affect PT, normalised ratio (INR), aPTT levels in people without known liver disease anticoagulant therapy. Method: Between July December 2021, patients past history were admitted LUMHS Hyderabad civil hospital minor surgical procedures (inguinal/umbilical hernia repair, caesarean section, rectal polyp excision, diagnostic cystoscopy). There 2274 all, 766 males 1508 females. According their chronological age, separated into three groups. sampled 268 men 22 women aged 0-14, 222 1335 15-50, 151 276 third range (over 50 year). Systemex CA-500 auto analyzer conduct analyses. Results: Males females considerably different INR values. Men between ages 15 more likely increased INR, readings than those 0 14. zero fourteen had lowest levels. 50, higher values over 50. based 95% confidence interval women, as well sexes ages. Conclusion: In arena, dearth has established that little effect Gender disparities clinically ranges must taken account. Keywords: Prothrombin Time, APTT, Outcomes