TOF-PET Image Reconstruction With Multiple Timing Kernels Applied on Cherenkov Radiation in BGO

نویسندگان

چکیده

Today Time-of-Flight (TOF), in PET scanners, assumes a single, well-defined timing resolution for all events. However, recent BGO-Cherenkov detectors, combining prompt Cherenkov emission and the typical BGO scintillation, can sort events into multiple kernels, best described by Gaussian mixture models. The number of photons detected per event impacts directly detector time signal rise time, which later be used to improve coincidence resolution. This work presents simulation toolkit applies spreads on coincident an image reconstruction that incorporates this information. A full cylindrical model was compared, terms contrast recovery contrast-to-noise ratio, against LYSO with 213 ps. Two approaches kernels were tested: 1) 2) decomposed simple kernels. exact component applied during simulation. Images reconstructed using provided similar mean value less noise than decomposed. typically, more iterations needed. Similarly, model, single TOF kernel, converged faster results indicate complexity slows down convergence. due higher sensitivity, ratio 26.4% better model.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

BGO as a hybrid scintillator / Cherenkov radiator for cost-effective time-of-flight PET.

Due to detector developments in the last decade, the time-of-flight (TOF) method is now commonly used to improve the quality of positron emission tomography (PET) images. Clinical TOF-PET systems based on L(Y)SO:Ce crystals and silicon photomultipliers (SiPMs) with coincidence resolving times (CRT) between 325 ps and 400 ps FWHM have recently been developed. Before the introduction of L(Y)SO:Ce...

متن کامل

Dynamic brain PET/MR using TOF reconstruction.

GE Healthcare, USA In a functional PET/MR study, it is difficult to get good temporal resolution of activity distribution from PET images because of the need to image for a certain length of time to get sufficient count statistics (image SNR). Time-of-flight (TOF) reconstruction can be used to increase PET images SNR and therefore increase the temporal resolution. Five patients were injected wi...

متن کامل

Accelerated time-of-flight (TOF) PET image reconstruction using TOF bin subsetization and TOF weighting matrix pre-computation.

Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, thereby the cross-dependencies of image voxels are reduced, which in turns results ...

متن کامل

PET Image Reconstruction

Positron emission tomography (PET) scanners collect measurements of a patient’s in vivo radiotracer distribution. These measurements are reconstructed into cross-sectional images. Tomographic image reconstruction forms images of functional information in nuclear medicine applications and the same principles can be applied to modalities such as X-ray computed tomography. This chapter provides a ...

متن کامل

Bayesian PET image reconstruction

We developed a maximum a posterior (MAP) reconstruction method for positron emission tomography (PET) image reconstruction incorporating magnetic resonance (MR) image information, with the joint entropy between the PET and MR image features serving as the regularization constraint. A non-parametric method was used to estimate the joint probability density of the PET and MR images. Using realist...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: IEEE transactions on radiation and plasma medical sciences

سال: 2021

ISSN: ['2469-7303', '2469-7311']

DOI: https://doi.org/10.1109/trpms.2020.3048642