Toll-like receptor 7 and 9 defects in common variable immunodeficiency
نویسندگان
چکیده
منابع مشابه
Toll-like receptor-9 gene polymorphism in common variable immunodeficiency.
Common variable immunodefi ciency (CVID) is a primary immunodeficiency involving a heterogeneous group of disorders characterized by recurrent bacterial infections and defi cient production of different classes of antibodies. The predisposing genetic factors associated with CVID remain unknown [1], although homozygous defects in ICOS or CD19 have been detected in a very small number of patients...
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Common variable immunodeficiency (CVID) is the most frequent clinically manifested primary immunodeficiency. According to clinical and laboratory findings, CVID is a heterogeneous group of diseases. Recently, the defects of molecules regulating activation and terminal differentiation of B lymphocytes have been described in some patients with CVID. In this study, we show the overview of deficien...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2009
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2009.05.019