Too Large or Too Small? Returns to Scale in a Retail Network

Born too small or too soon.

In The Lancet Global Health, Anne Lee and colleagues from the Child Health Epidemiology Reference Group (CHERG) make an important contribution to our understanding of the global burden of intrauterine growth restriction. What is new in this work is the evidence that the majority of growth-restricted neonates (assessed with the proxy of small-forgestational-age birth) weigh 2500 g or more at bir...

Low-birthweight baby: Born too soon or too small

Research into gut microbiome is being actively pursued now which has been discussed under the section, ‘Interactions of Bile Acids and the Gut Microbiome’. Interactions of bile acid metabolism and gut microbiota in patients with cirrhosis are discussed in this section. Similar hypotheses are being looked at in the pathogenesis of inflammatory bowel diseases and hepatocellular carcinoma in these...

Too much or too little

The global effort to understand the molecular drivers of cancer onset and progression is now coming to fruition with the identification of specific genomic and epigenomic events that influence signaling through key oncogenic pathways. Genetic studies using inducible expression of the critical growth controlling oncogenes MYC, RAS, PI3K and AKT have shown unequivocally that, in conjunction with ...

Gastrografin-based conservative approach to small bowel obstructions: too far from a daily use

As known, small bowel obstruction is one of the most common emergencies in general surgery carrying a not negligible rate of morbidity and financial expenditures as far as high social impact . Peritoneal adhesions are the leading cause of intestinal obstruction up to 74% of cases. In spite of increasing incidence worldwide, current management still presents some “blind corners”, whose aspects s...

SOME NOi-PARAMETRIC TESTS OF WHETHER THE UROIST OBfiERVAnONS OF A SET ARE TOO LARGE OR TOO SMALL By