Topical Azithromycin and Oral Doxycycline Therapy of Meibomian Gland Dysfunction

The effect of low-dose doxycycline therapy in chronic meibomian gland dysfunction.

PURPOSE The aim was to investigate the effect of low dose doxycycline (20 mg) therapy in patients with chronic meibomian gland dysfunction that were refractory to conventional therapy. METHODS The randomized prospective study enrolled 150 patients (300 eyes) who have chronic meibomian gland dysfunction and who didn't respond to lid hygiene and topical therapy for more than 2 months. All topic...

Topical diquafosol for patients with obstructive meibomian gland dysfunction

AIMS To evaluate the effect of topical diquafosol in patients with meibomian gland dysfunction (MGD) using tear film parameters and quantitatively analyse the meibomian gland morphology. SUBJECTS AND METHODS The subjects were 19 eyes of 10 patients diagnosed with obstructive MGD. All subjects were given 3% diquafosol ophthalmic solution with instructions to use one drop four times a day. Ocul...

Meibomian gland dysfunction

Meibomian gland dysfunction.

Blepharitis is probably the most common disease entity seen in the general ophthalmologist's office. A significant proportion of these cases are secondary to meibomian gland disease. This review outlines our knowledge of the histopathology, lipid abnormalities and role of microorganisms in meibomian gland dysfunction. We will also review the physiology of meibomian gland secretion and present m...

Meibomian Gland Dysfunction and Hypercholesterolemia

High cholesterol is a known risk factor for ischemic heart, cerebrovascular, and peripheral vascular disease. Previous studies have postulated that hypercholesterolemia (defined as total cholesterol of at least 200 mg/dL) also plays a role in the development of meibomian gland dysfunction (MGD). In this observational, case-control study, Pinna et al. investigated the correlation between MGD and...