Toward a general evolutionary theory of oncogenesis

Toward a general evolutionary theory of oncogenesis

We propose an evolutionary framework, the barrier theory of cancer, which is based on the distinction between barriers to oncogenesis and restraints. Barriers are defined as mechanisms that prevent oncogenesis. Restraints, which are more numerous, inhibit but do not prevent oncogenesis. Processes that compromise barriers are essential causes of cancer; those that interfere with restraints are e...

Toward Evolutionary Innovation Theory

Abstract: Innovations, commercialized by new or old established firms, located at the core of industrial renewal process. The innovation concept has suffered transformations, along with the evolution of the models that try to explain and understand the innovation process. The innovative process corresponds to all activities that generate technological changes and the dynamic interaction between...

TOWARD EVOLUTIONARY INNOVATION THEORY

Innovations, commercialized by new or old established firms, located at the core of industrial renewal process. The innovation concept has suffered transformations, along with the evolution of the models that try to explain and understand the innovation process. The innovative process corresponds to all activities that generate technological changes and the dynamic interaction between them, not...

Toward a Hermeneutical Evolutionary Theory

Toward a theory of evolutionary computation.

We outline a theory of evolutionary computation using a formal model of evolutionary computation--the Evolutionary Turing Machine--which is introduced as the extension of the Turing Machine model. Evolutionary Turing Machines provide a better and a more complete model for evolutionary computing than conventional Turing Machines, algorithms, and Markov chains. The convergence and convergence rat...