Trans-generation inheritance of methylation patterns in a tobacco transgene following a post-transcriptional silencing event
نویسندگان
چکیده
منابع مشابه
DNA methylation and chromatin structure affect transcriptional and post-transcriptional transgene silencing in Arabidopsis
In plants, transgenes can be silenced at both the transcriptional [1] and post-transcriptional levels [2]. Methylation of the transgene promoter correlates with transcriptional gene silencing (TGS) [3] whereas methylation of the coding sequence is associated with post-transcriptional gene silencing (PTGS) [4]. In animals, TGS requires methylation and changes in chromatin conformation [5]. The i...
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Sense transgene-induced post-transcriptional gene silencing (S-PTGS) is thought to be a type of RNA silencing in which ARGONAUTE1 directs the small interfering RNA (siRNA)-mediated cleavage of a target mRNA in the cytoplasm. Here, we report that the altered splicing of endogenous counterpart genes is a main cause for the reduction of their mature mRNA levels. After the S-PTGS of a tobacco endop...
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Hybridization in plants leads to transinteractions between the parental genomes and epigenomes that can result in changes to both 24 nt siRNA and cytosine methylation ((m)C) levels in the hybrid. In Arabidopsis the principle processes altering the hybrid methylome are Trans Chromosomal Methylation (TCM) and Trans Chromosomal deMethylation (TCdM) in which the (m)C pattern of a genomic segment at...
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Philosophy and The Human Inheritance in a Post-Western World
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ژورنال
عنوان ژورنال: The Plant Journal
سال: 2008
ISSN: 0960-7412,1365-313X
DOI: 10.1111/j.1365-313x.2008.03475.x