Transcribing the Cross-Talk of Cytokine-Induced Tetrahydrobiopterin Synthesis in Endothelial Cells
نویسندگان
چکیده
منابع مشابه
Transcribing the cross-talk of cytokine-induced tetrahydrobiopterin synthesis in endothelial cells.
Tetrahydrobiopterin (BH4) is an essential cofactor required for the production of nitric oxide by each of the nitric oxide synthase (NOS) isoforms (see review1). Synthesis of BH4 involves a multistep process in which GTP cyclohydrolase I (GTPCH I) is the rate-limiting enzyme required for the initial step in conversion of guanosine-5 triphosphate (GTP) to BH4. The importance of BH4 has been even...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2005
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000156078.12390.44