Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complex
نویسندگان
چکیده
منابع مشابه
Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complex
The RNA exosome complex functions in both the accurate processing and rapid degradation of many classes of RNA. Functional and structural analyses indicate that RNA can either be threaded through the central channel of the exosome or more directly access the active sites of the ribonucleases Rrp44 and Rrp6, but it was unclear how many substrates follow each pathway in vivo. We used CRAC (UV cro...
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ژورنال
عنوان ژورنال: PLOS Genetics
سال: 2017
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1006699