Transnuclear CD 8 T cells specific for the immunodominant epitope Gra6 lower acute‐phase Toxoplasma gondii burden
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چکیده
منابع مشابه
Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute‐phase Toxoplasma gondii burden
We generated a CD8 T-cell receptor (TCR) transnuclear (TN) mouse specific to the Ld -restricted immunodominant epitope of GRA6 from Toxoplasma gondii as a source of cells to facilitate further investigation into the CD8 T-cell-mediated response against this pathogen. The TN T cells bound Ld -Gra6 tetramer and proliferated upon unspecific and peptide-specific stimulation. The TCR beta sequence o...
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ژورنال
عنوان ژورنال: Immunology
سال: 2016
ISSN: 0019-2805,1365-2567
DOI: 10.1111/imm.12643