Treatment of Pulmonary Embolism With Rivaroxaban: Outcomes by Simplified Pulmonary Embolism Severity Index Score from a Post Hoc Analysis of the EINSTEIN PE Study

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Treatment of Pulmonary Embolism With Rivaroxaban: Outcomes by Simplified Pulmonary Embolism Severity Index Score from a Post Hoc Analysis of the EINSTEIN PE Study

OBJECTIVES The objective was to assess adverse outcomes in relation to the simplified Pulmonary Embolism Severity Index (PESI) score in patients treated with rivaroxaban or standard therapy in the phase III EINSTEIN PE study and to evaluate the utility of the simplified PESI score to identify low-risk pulmonary embolism (PE) patients. METHODS A post hoc analysis of EINSTEIN PE data was perfor...

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Predictive value of troponins and simplified pulmonary embolism severity index in patients with normotensive pulmonary embolism

BACKGROUND To investigate whether 2 cardiac troponins [conventional troponin-T(cTnT) and high sensitive troponin-T(hsTnT)] combined with simplified pulmonary embolism severity index (sPESI), or either test alone are useful for predicting 30-day mortality and 6 months adverse outcomes in patients with normotensive pulmonary embolism(PE). METHODS The prospective study included 121 consecutive p...

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Rivaroxaban for the Treatment of Pulmonary Embolism

With the advent of new oral anticoagulants (NOACs) for the treatment of deep-vein thrombosis (DVT) and/or pulmonary embolism (PE), a new era of oral anticoagulation for patients with venous thromboembolism (VTE) has begun. Rivaroxaban is the first NOAC to receive regulatory approval for the acute and continued treatment of DVT and PE, and for the secondary prevention of VTE. Here, the clinical ...

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The prognostic value of pulmonary embolism severity index in acute pulmonary embolism: a meta-analysis

BACKGROUND Prognostic assessment is important for the management of patients with acute pulmonary embolism (APE). Pulmonary Embolism Severity Index (PESI) and simple PESI (sPESI) are new emerged prognostic assessment tools for APE. The aim of this meta-analysis is to assess the accuracy of the PESI and the sPESI to predict prognostic outcomes (all-cause and PE-related mortality, serious adverse...

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Pulmonary Embolism Severity Index (PESI) and Simplified PESI

REFERENCES 1 Moores L, Zamarro C, Gómez V, et al. Changes in PESI score predict mortality in intermediate-risk patients with acute pulmonary embolism. Eur Respir J 2013; 41: 354–359. 2 Aujesky D, Smith KJ, Cornuz J, et al. Cost-effectiveness of lowmolecular-weight heparin for treatment of pulmonary embolism. Chest 2005; 128: 1601–1610. 3 Erkens PM, Gandara E, Wells PS, et al. Does the Pulmonary...

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ژورنال

عنوان ژورنال: Academic Emergency Medicine

سال: 2015

ISSN: 1069-6563,1553-2712

DOI: 10.1111/acem.12615