Treatment with Selemax®, a selenium-enriched yeast, ameliorates experimental arthritis in rats and mice
نویسندگان
چکیده
منابع مشابه
An Experimental Design for Production of Selenium-Enriched Yeast
Selenium (Se) enriched yeast, produced by growing of Saccharomyces cerevisiae in Se rich media, is a recognized source of organic food-form of Se. Effects of culture conditions (temperature, fermentation time, initial pH value, shaking speed, as well as time and concentration of Se added to medium) on the bioaccumulation of Se in yeast were investigated by Plackett-Burman design in this paper. ...
متن کاملExperimental arthritis in mice with Mycoplasma pulmonis.
A Mycoplasma pulmonis strain, recovered from the arthritic joints of mice employed in the serial passage of a chemically induced tumor, was found to be arthritogenic for mice under experimental conditions. Some joint involvement occurred in all mice challenged intravenously with this strain, and M. pulmonis was recovered frequently from the enlarged joints. The arthritis was migratory, appearin...
متن کاملIntraarticular overexpression of Smad7 ameliorates experimental arthritis
Rheumatoid arthritis (RA) and Crohn's disease (CD) are autoimmune disorders with a crosstalk between their pathogenesis such as increased expression of TNF in the target organs. Despite a successful clinical trial with an oral Smad7 antisense oligonucleotide in CD, intraarticular (i.a.) modulation of Smad7 expression has not been performed in rheumatoid joint yet. In this study, contradictory t...
متن کاملSelenium-Enriched B. longum Inhibits Tumor Growth in Mice
Bifidobacterium longum (B. longum) is a lactic acidproducing bacterium that grows naturally in the human gastrointestinal tract and defends the host against viral infection (Otles et al., 2003; Picard et al., 2005). As an anaerobe, B. longum can selectively germinate and proliferate in the hypoxic regions of solid tumors (Yazawa et al., 2000). Previous studies showed that B. longum had anticanc...
متن کاملIL-12p40 Homodimer Ameliorates Experimental Autoimmune Arthritis.
IL-23 is the key cytokine that induces the expansion of Th17 cells. It is composed of p19 and p40 subunits of IL-12. The p40 subunit binds competitively to the receptor of IL-23 and blocks its activity. Our aim was to assess the preventive and therapeutic effect of the IL-12p40 homodimer (p40)2 subunit in autoimmune arthritis animal models. In the current study, using IL-1R antagonist-knockout ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 2012
ISSN: 0007-1145,1475-2662
DOI: 10.1017/s0007114512000013