Trisomy 21: 91% detection rate using second-trimester ultrasound markers
نویسندگان
چکیده
منابع مشابه
Meta-analysis of second-trimester markers for trisomy 21.
OBJECTIVE To summarize by meta-analysis the accumulated data on the screening performance of second-trimester sonographic markers for fetal trisomy 21. METHODS We conducted a literature search to identify studies between 1995 and September 2012 that provided data on the incidence of sonographic markers in trisomy 21 and euploid fetuses at 14-24 weeks' gestation. Weighted independent estimates...
متن کاملSecond-trimester screening for trisomy-21 using prefrontal space ratio.
OBJECTIVE To investigate the potential value of prefrontal space ratio (PFSR) in second-trimester screening for trisomy-21. METHODS A retrospective study utilizing stored midsagittal two-dimensional images of fetal profiles in 240 euploid and 45 trisomy-21 pregnancies at 16(+0)-23(+6) weeks' gestation. The vertical distance between the leading edge of the skull and that of the skin (D1) and t...
متن کاملSecond-trimester genetic sonography after first-trimester combined screening for trisomy 21.
OBJECTIVE The purpose of this study was to evaluate the trisomy 21 screening performance of the first-trimester combined test followed by second-trimester genetic sonography. METHODS This retrospective cohort study included all women with singleton pregnancies undergoing combined screening followed by genetic sonography at 17 to 21 weeks from January 1, 2005, to January 31, 2008. Combined tes...
متن کاملFirst Trimester Diagnosis of Trisomy-21 Using Artificial Neural Networks
A chromosomal disorder caused by the presence of all or part of an extra 21st chromosome is known as the Down syndrome, or trisomy 21, or trisomy G. In the last fifteen years it has become possible to observe these features by ultrasound examination in the third month of intrauterine life. About 75% of trisomy 21 fetuses have absent nasal bone. In the present work, neural network schemes that h...
متن کاملFirst-trimester screening for trisomy 21 using alpha-fetoprotein.
OBJECTIVE To investigate the potential value of adding maternal serum alpha-fetoprotein (AFP) to free β-human chorionic gonadotropin (β-hCG) and PAPP-A and fetal nuchal translucency (NT) thickness in first-trimester screening for trisomy 21. METHODS In this case control study, serum AFP was measured in 100 trisomy 21 and 1,500 euploid pregnancies in which screening for trisomy 21 had been per...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2000
ISSN: 0960-7692
DOI: 10.1046/j.1469-0705.2000.00203.x