TRPC3/6/7 Knockdown Protects the Brain from Cerebral Ischemia Injury via Astrocyte Apoptosis Inhibition and Effects on NF-кB Translocation
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Bicyclol protects cardiomyocytes from apoptosis in ischemia/reperfusion injury via inhibition of TLR4/NF-κB pathway
Toll-like receptor 4 (TLR4)-mediated apoptosis plays a critical role in the etiology and pathogenesis of myocardial ischemia/reperfusion (I/R) injury (MIRI). Bicyclol has been shown to possess a variety of pharmacological effects, but its anti-apoptotic property has garnered particular interest. The aim of this study is to elucidate the cardioprotective effect of bicyclol in I/R injury, and to ...
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ژورنال
عنوان ژورنال: Molecular Neurobiology
سال: 2016
ISSN: 0893-7648,1559-1182
DOI: 10.1007/s12035-016-0227-2