Tumor-associated macrophages (TAMs): clinical-pathological parameters in squamous cell carcinomas of the lower lip

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Tumor-associated macrophages (TAMs): clinical-pathological parameters in squamous cell carcinomas of the lower lip.

The objective of this study was to analyze the presence of tumor-associated macrophage (TAM) subpopulations M1 and M2 in squamous cell carcinoma of the lower lip (SCCLL) by immunohistochemitry, and to evaluate the possible role of these subtypes in the development of regional lymph node metastasis and their association with clinical and pathological parameters. Forty-two cases of SCCLL were div...

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Clinical-pathological parameters in squamous cell carcinoma of the tongue.

The correlation between TNM classification and histological scores of malignancy, and the correlation of these parameters with the prognosis was evaluated in 16 cases of squamous cell carcinoma of the tongue. The cases were selected from the files of "Dr. Luiz Antônio" Cancer Hospital, Natal, RN, Brazil. After analysis of the patients' records, the data concerning TNM classification and prognos...

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Immunohistochemical analysis of FoxP3+ regulatory T cells in lower lip squamous cell carcinomas.

The aim of this study was to determine the number of FoxP3+ regulatory T (Treg) cells in the microenvironment of lower lip squamous cell carcinomas (LLSCCs) and to correlate the findings with clinicopathological parameters (tumor size/extent, regional lymph node metastasis, clinical stage, and histopathological grade of malignancy). Fifty cases of LLSCC were selected. Lymphocytes exhibiting nuc...

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Angiogenesis and Tumor-Associated Macrophages in Different Grades of Oral Squamous Cell Carcinoma, Verrucous Carcinoma and Epithelial Dysplasia via Immunohistochemical Assessment of Expression of CD34 and CD68 Markers

Background:Squamous cell carcinoma (SCC) is the most common malignancy of the oral cavity, which is highly invasive. Verrucous carcinoma (VC) is the low-grade form of SCC. Epithelial dysplasia (ED) also has a malignant potential. This immunohistochemical (IHC) study aimed to assess angiogenesis and the presence of tumor-associated macrophages (TAMs) in SCC, VC and ED to determi...

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Immunohistochemical expression of E-cadherin and CD44v6 in squamous cell carcinomas of the lower lip and tongue.

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ژورنال

عنوان ژورنال: Brazilian Oral Research

سال: 2016

ISSN: 1806-8324

DOI: 10.1590/1807-3107bor-2016.vol30.0095