Twenty years of metabonomics: so what has metabonomics done for toxicology?
نویسندگان
چکیده
منابع مشابه
Metabonomics in toxicology: a review.
Metabonomics and its many pseudonyms (metabolomics, metabolic profiling, etc.) have exploded onto the scientific scene in the past 2 to 3 years. Nowhere has the impact been more profound than within the toxicology community. Within this community there exists a great deal of uncertainty about whether metabonomics is something to count on or just the most recent technological flash in the pan. M...
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This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
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We provide an overview of how the underlying philosophy of chemometrics is integrated throughout metabonomic studies. Four steps are demonstrated: (1) definition of the aim, (2) selection of objects, (3) sample preparation and characterization, and (4) evaluation of the collected data. This includes the tools applied for linear modeling, for example, Statistical Experimental Design (SED), Princ...
متن کاملClinical and Epidemiological Metabonomics
1College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan Province, China 2Computational Medicine Research Group, Institute of Clinical Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, P.O. Box 5000, 90014 University of Oulu, Oulu, Finland 3NMRMetabonomics Laboratory, Department of Biosciences, University of Eastern Finland, 70211 Kuop...
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Comparasite is a database for comparative studies of transcriptomes of parasites. In this database, each data is defined by the full-length cDNAs from various apicomplexan parasites. It integrates seven individual databases, Full-Parasites, consisting of numerous full-length cDNA clones that we have produced and sequenced: 12 484 cDNA sequences from Plasmodium falciparum, 11 262 from Plasmodium...
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ژورنال
عنوان ژورنال: Xenobiotica
سال: 2019
ISSN: 0049-8254,1366-5928
DOI: 10.1080/00498254.2019.1697015