Twisting in a crowd
نویسندگان
چکیده
منابع مشابه
Twisting in a crowd
The scenery of the nucleus The nucleoplasm is no less dense, even though it contains neither membrane nor rigid filament. However, it contains one remarkable type of filament, the DNA, which, for a mammalian cell with a small nucleus, can account for close to 10% (100 mg m1-1) of the nuclear mass (including water). This is a very high concentration much higher than that generally used for exper...
متن کاملWater in a crowd.
In many situations, form biology to geology, water occurs not as the pure bulk liquid but rather in nanoscopic environments, in contact with interfaces, interacting with ionic species, and interacting with large organic molecules. In such situations, water does not behave in the same manner as it does in the pure bulk liquid. Water dynamics are fundamental to many processes such as protein fold...
متن کاملFolding in a crowd
JCB • VOLUME 169 • NUMBER 1 • 2005 16 Folding in a crowd roteins fold better in a crowd, as predicted by a biophysical model from Margaret Cheung, Dmitri Klimov, and D. Thirumalai (University of Maryland, College Park, MD). Interactions between a protein and large nearby molecules produce repulsive forces at distances that can be as large as the protein itself. The group modeled the energetic e...
متن کاملStrategies in crowd and crowd structure
In an emergency situation, imitation of strategies of neighbours can lead to an order-disorder phase transition, where spatial clusters of pedestrians adopt the same strategy. We assume that there are two strategies, cooperating and competitive, which correspond to a smaller or larger desired velocity. The results of our simulations within the Social Force Model indicate that the ordered phase ...
متن کاملTwisting chromatin in stem cells.
How transcriptional output is orchestrated in mammalian genomes is an area of intense research. The structural organization within the nucleus and the physical association between regulatory elements are considered critical components in this regulation. Recent work published in Nature (de Wit et al, 2013) applied the Circular Chromosome Conformation Capture (4C) method at high resolution in pl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Trends in Cell Biology
سال: 1993
ISSN: 0962-8924
DOI: 10.1016/0962-8924(93)90182-z