Two T7-like Bacteriophages, K5-2 and K5-4, Each Encodes Two Capsule Depolymerases: Isolation and Functional Characterization
نویسندگان
چکیده
منابع مشابه
Therapeutic Application of Phage Capsule Depolymerases against K1, K5, and K30 Capsulated E. coli in Mice
Capsule depolymerase enzymes offer a promising class of new antibiotics. In vivo studies are encouraging but it is unclear how well this type of phage product will generalize in therapeutics, or whether different depolymerases against the same capsule function similarly. Here, in vivo efficacy was tested using cloned bacteriophage depolymerases against Escherichia coli strains with three differ...
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R(C4, K4) = 10 (see [2]) R(C4, K5) = 14 (see [3]) R(C5, K4) = 13, R(C5, K5) = 17 (see [5, 6]) R(Cn, K3) = 2n − 1 (n > 3) (see [4, 7]). In [10], we proved that R(Cn, K4) = 3(n − 1) + 1 (n ≥ 4). In this paper, we will prove that R(Cn, K5) = 4(n − 1)+ 1 (n = 6, 7). The following notations will be used in this paper. If G is a graph, the vertex set (resp. edge set) of G is denoted by V (G) (resp. E...
متن کاملThe Ramsey Number r(K5-P3,K5)
For two given graphs G1 and G2, the Ramsey number r(G1, G2) is the smallest integer n such that for any graph G of order n, either G contains G1 or the complement of G contains G2. Let Km denote a complete graph of order m and Kn −P3 a complete graph of order n without two incident edges. In this paper, we prove that r(K5 − P3,K5) = 25 without help of computer algorithms.
متن کاملThe non-anticoagulant heparin-like K5 polysaccharide derivative K5-N,OSepi attenuates myocardial ischaemia/reperfusion injury
Heparin and low molecular weight heparins have been demonstrated to reduce myocardial ischaemia/reperfusion (I/R) injury, although their use is hampered by the risk of haemorrhagic and thrombotic complications. Chemical and enzymatic modifications of K5 polysaccharide have shown the possibility of producing heparin-like compounds with low anticoagulant activity and strong anti-inflammatory effe...
متن کاملK5-Subdivisions in graphs containing K-4
Seymour and, independently, Kelmans conjectured in the 1970s that every 5-connected nonplanar graph contains a subdivision of K5. In this paper, we prove this conjecture for graphs containing K− 4 . AMS Subject Classification: 05C
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-04644-2