Type I error control in biomarker-stratified clinical trials
نویسندگان
چکیده
منابع مشابه
Type I error rate control in adaptive designs for confirmatory clinical trials with treatment selection at interim.
Interest in confirmatory adaptive combined phase II/III studies with treatment selection has increased in the past few years. These studies start comparing several treatments with a control. One (or more) treatment(s) is then selected after the first stage based on the available information at an interim analysis, including interim data from the ongoing trial, external information and expert kn...
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ژورنال
عنوان ژورنال: Trials
سال: 2015
ISSN: 1745-6215
DOI: 10.1186/1745-6215-16-s2-o84