Type II mixed cryoglobulinaemia, hepatitis C virus infection, and glomerulonephritis

Parvovirus B19 infection, hepatitis C virus infection, and mixed cryoglobulinaemia.

BACKGROUND Infection with human parvovirus B19 (B19) has been reported in a few patients with various vasculitis syndromes. Mixed cryoglobulinaemia (MC), a model of small vessel size vasculitis, may result from numerous infectious diseases, particularly hepatitis C virus (HCV) infection. AIM To assess the prevalence of seric B19 infection markers in a large series of patients with MC, with or...

Hepatitis C virus infection, cryoglobulinaemia, and beyond.

Hepatitis C virus (HCV) infection is the major cause of mixed cryoglobulinaemia (MC), an immune complex (IC)-mediated systemic vasculitis mainly involving the small blood vessels. The precise mechanism of cryoprotein production is currently unknown. HCV virions and non-enveloped core protein participate in the formation of cold-insoluble ICs. Cryoglobulinaemic patients represent a distinct HCV-...

Hepatitis C virus, mixed cryoglobulinaemia and non-Hodgkin's lymphoma.

The aetiology of non-Hodgkin's lymphomas remains a controversial matter, but, recently, evidence has emerged showing that these neoplastic aberrations of the immune system may be due to viruses, at least in some cases. In fact, patients affected by an inherited immune deficiency, and those presenting disease characterized by autoimmune dysfunctions, show an increased risk for the development of...

Mixed cryoglobulinaemia after hepatitis C virus: more and less ambiguity.

Bronchoalveolar lavage in mixed cryoglobulinaemia associated with hepatitis C virus.

In order to evaluate the presence of an inflammatory process of the lower respiratory tract in patients with mixed cryoglobulinaemia (MC) associated with hepatitis C virus (HCV), bronchoalveolar lavage (BAL) was performed in 16 non-smoking females free of clinical pulmonary symptoms and with normal chest roentgenograms. Pulmonary function tests including diffusion capacity for carbon monoxide (...