Typhlitis: a neutropenic complication

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Typhlitis: a neutropenic complication.

DESCRIPTION ‘Typhlitis’ describes enterocolitis of the ileocaecal region seen commonly in neutropenic patients. As compared with other malignant conditions, acute myeloid leukaemia (AML) is most often associated with typhlitis. The pathogenesis of typhlitis probably involves a combination of factors, including mucosal injury by cytotoxic drugs, profound neutropenia and impaired host defence to ...

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Typhlitis as a complication of alemtuzumab therapy.

Alemtuzumab is a humanized monoclonal antibody directed against lymphocytes through the CD-52 receptor, an antigen being found on > 95% of peripheral blood lymphocytes and monocytes, and to a smaller extent on granulocytes. It is an effective immunotherapeutic agent in patients with malignancies such as non-Hodgkin lymphoma, B cell chronic lymphocytic leukemia and T cell pro- lymphocytic leukem...

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Successful medical management of neutropenic enterocolitis (typhlitis) in a child with acute lymphoblastic leukemia.

We report a case of acute lymphoblastic leukemia that was complicated by neutropenic enterocolitis (typhlitis) during the initial period of remission-induction chemotherapy. The patient's clinical symptoms resolved after aggressive treatment with intravenous fluids and electrolytes, nasogastric decompression, bowel rest, total parenteral nutrition, broad-spectrum antibiotics, and granulocyte co...

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Typhlitis in a post-chemotherapy lymphoma patient; images in clinical medicine

Typhlitis, also known as neutropenic enterocolitis, occurs primarily in severely immunosuppressed patients undergoing chemotherapy for haemathological and solid tumors. We report a case of a 57 years-old patient who presented typhlitis as a complication during chemotherapy.

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ژورنال

عنوان ژورنال: Case Reports

سال: 2012

ISSN: 1757-790X

DOI: 10.1136/bcr.02.2012.5815